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Multiple discrete papules or macerated patches present on the vulva and perianal area
  • Single lesion
  • Hyperkeratosis, parakeratosis, and acanthotic epidermis
  • Suprabasal acantholysis with dyskeratosis
  • Little or no inflammation.
  • Work-Up Considerations:

    • Skin biopsy and correlation of histologic findings with clinical and family history.
    • Cultures to rule out superimposed infection

    Treatment:

    • Treatment is difficult and patient reassurance is often adequate
    • If treatment is desired, topical tretinoin may be helpful
    • Surgical removal of localized lesions or electrocautery can also be helpful.
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