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This is a histologic subtype of actinic keratosis that presents as erythematous scaly patches on sun-exposed areas
  • Crowding and atypia of keratinocytes in lower layers of the epidermis with scattered foci of acantholysis.

    Work-Up Considerations:

    • Actinic keratoses can usually be diagnosed clinically
    • Recurrent or recalcitrant lesions, or lesions suspicious for skin cancer should be biopsied for histologic evaluation.

    Treatment:

    • Sun protection, sun avoidance, daily broad spectrum sunscreen application, and regular clinical follow-up should be advocated for all patients.
    • Cryotherapy
    • Topical 5-fluorouracil
    • Topical imiquimod
    • Photodynamic therapy
    • Topical adapalene
    • Topical diclofenac
    • Topical ingenol mebutate
    • Some other therapeutic modalities that may be tried include: curettage, ablative laser therapy, chemical peels, as well as dermabrasion.
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